Healthy adults who underwent day-case colonoscopy day-case colonoscopy, recovery time, lidocaine, propofol-lidocaine, propofol-fentanyl
Conditions
Interventions
fentanyl 1 ug/kg intravenously 2 min prior to induction with propofol 1 mg/kg then maintain deep sedation dept with intermittent propofol 10-30 mg/kg iv when RSS less than 5, HR increased by more tha
Active Comparator Drug,Experimental Drug
propofol-fentanyl,propofol-lidocaine
Sponsors
Kanittha Nakkarin
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Adult aged 18 to 64 years and of either sex 2. American Society of Anesthesiologists (ASA) physical status I and II who underwent colonoscopy day-case surgery
Exclusion criteria
Exclusion criteria: 1. Patients who refused to participate or could not communicate with the researcher, 2. Contraindication to any study drugs, 3. Pregnancy or lactation, 4. Cardiovascular disease such as ischemic heart disease, hypertension, or arrhythmia, 5. Body mass index (BMI) > 30 kg/m2, 6. Obstructive sleep apnea (OSA), 7. Chronic obstructive pulmonary disease (COPD), 8. History of epilepsy or seizure disorder, 9. Using hypnotic drugs, 10. GFR < 45 ml/min/1.73 m2, 11. cirrhosis Child-Pugh B and C, 12. Family history of suspected malignant hyperthermia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recovery time end of procedure time between end colonoscopy to awake with RSS 2 | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of hypotension, desaturation, bradycardia, hemodynamic change, propofol consumption intraoperative MAP drop more than 20% from baseline, SpO2 less than 95, HR less than 50 bpm | — |
Countries
Thailand
Contacts
Public ContactKanittha Nakkarin
Department of Anesthesiology, Kumphawapi hospital, Thailand
Outcome results
None listed