Perioperative myocardial injury (PMI), Myocardial infarction, Hip and Knee Surgery High-sensitivity Troponin T, Perioperative myocardial injury, Hip replacement, Knee replacement, Elderly, RCRI
Conditions
Interventions
Patients ages 65 years and older undergoing hip and knee surgery in Ramathibodi hospital
Diagnostic
Patients undergoing hip and knee surgery
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 65 years and older 2. Undergoing total knee replacement, total hip replacement, or hip fracture surgery (elective or emergency) 3. Receiving general or regional anesthesia 4. Admitted to the hospital for at least 1 day postoperatively 5. Willing to participate and sign informed consent (or by legal representative)
Exclusion criteria
Exclusion criteria: Patients who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of hs-Trop-T in predicting Perioperative Myocardial Injury (PMI) Within 48 hours post-operation (Day 1 and Day 2). Comparison of Area Under the Curve (AUC) between hs-Trop-T and RCRI score. PMI is defined as hs-Trop-T elevation 14 ng/L above baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Perioperative Myocardial Injury (PMI) Within 48 hours post-operation. Percentage of patients with PMI.,30-day Major Adverse Cardiac Events (MACE) 30 days post-operation. Composite of myocardial ischemia, myocardial infarction, heart failure, arrhythmia requiring treatment, stroke, and cardiac arrest.,30-day Mortality 30 days post-operation. All-cause death. | — |
Countries
Thailand
Contacts
Public ContactKhachiwan Prateeppichai
Department of Anesthesiology Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed