1. hemodynamic stability after induction at various time points 2. LMA insertion 3. first-attempt success rate propofol
Conditions
Interventions
propofol 2 mg per kg intravenous administered for induction for I g-gel LMA insertion, premedicated with fentanyl 1 mcg per kg,propofol 1 mg per kg combined with etomidate 0.2 mg per kg, premedicated
Active Comparator Drug,Active Comparator Drug
propofol 2 mg per kg ,propofol 1 mg per kg combined with etomidate 0.2 mg per kg
Sponsors
Kanittha Nakkarin
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I and II, aged 18 to 64 years and of either sex who underwent elective surgery under general anesthesia with I-gel LMA.
Exclusion criteria
Exclusion criteria: patients who refused to participate or could not communicate with the researcher; contraindication to any study drugs; pregnancy or lactation; cardiovascular disease such as ischemic heart disease, hypertension, or arrhythmia; existing pathology in the pharynx or larynx; limited mouth opening (less than 2.5 cm); Mallampati score 3 and 4; difficult airway; body mass index (BMI) more than 30 kg/m2; full stomach; reactive airway disease; known primary or secondary adrenal insufficiency; use of steroid medication by any route; sepsis; history of epilepsy or seizure disorder; GFR less than 30 ml/min/1.73 m2; and cirrhosis Child-Pugh B and C
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic stability before induction (Tb), 1 minute after induction (T0), after successful LMA insertion (T1), and 3 (T2), 5 (T3), and 10 (T4) minutes after successful LMA insertion MAP, SBP, DBP, HR | — |
Secondary
| Measure | Time frame |
|---|---|
| LMA insertion conditions, first-attempt success rate the first attempt at I-gel insertion jaw relaxation, patient response (gagging/coughing, patient movement, laryngospasm), overall insertion conditions, number of insertion attempts) | — |
Countries
Thailand
Contacts
Public ContactKanittha Nakkarin
Department of Anesthesiology, Kumphawapi Hospital
Outcome results
None listed