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Effects of Transcutaneous electrical stimulation and Cryotherapy Prior to Exercises on Patellofemoral Pain Patients: Randomized Controlled Trial

Effects of TENs and Cryotherapy Prior to Exercises on Patellofemoral Pain Patients: Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260110006
Enrollment
75
Registered
2026-01-10
Start date
2024-07-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral Pain Patellofemoral pain syndrome, Transcutaneous electrical stimulation, Cryotherapy, Arthrogenic Muscle Inhibition, Isokinetic muscle strength, Isometric muscle strength, Rate or torque development

Interventions

EV-806A digital TENs is a battery-operated pulse generator device used. Adhesive electrodes are placed on the superior and inferior anterolateral and anteromedial border of patella, spaced apart by ar
Active Comparator Device,Active Comparator Device,No Intervention Other
Transcutaneous electrical nerve stimulation (TENs),Cryotherapy,Exercises only

Sponsors

Thai red cross society
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Present and reproduction of peripatellar or retropatellar pain in squatting and at least one functional task (running, kneeling, jumping, climbing or descending stairs, sitting for a long time, sitting with knees flexed, or other functional activities loading the patellofemoral joint in flexed position) 2. Ongoing patellar pain for at least 1 months 3. PFP with a pain severity of 40-79/100 (activity related) on visual analog scale (0 no pain, 100 intolerable pain) 4. Not participating in any PFP treatment within previous 1 month 5. Age 20-60 years old 6. BMI < 30 kg/m2 7. Participating in aerobics or athletic activities at least three times a week for at least 30 minutes. 8. Able to obtain Femoral H-reflex. 9. Able to use ice pack at home

Exclusion criteria

Exclusion criteria: 1. Signs or symptoms other distinct knee pathologies, which potentially cause anterior knee pain, such as iliotibial band friction syndrome, tendinitis, neuromas, intra-articular pathology including osteoarthritis, rheumatoid arthritis, traumatic injuries (such as injured ligaments, meniscal tears, patellar fractures and patellar luxation), plica syndromes and more rarely occurring pathologies 2. History of hip, knee, or ankle joint surgery 3. Hip, knee, or ankle joint deformity/dislocation 4. History of traumatic, inflammatory or infectious pathology in the lower extremities or any internal derangements 5. Concurrent lower limb injuries 6. Evidence of active inflammation (redness, swelling and edema) 7. Contraindication to TENs such as active malignancy or active infection at electrode placement site or contraindication to cryotherapy such as impaired circulation, peripheral vascular disease, hypersensitive to cold, skin anesthesia, open wound or skin conditions and local infection

Design outcomes

Primary

MeasureTime frame
Knee pain (VAS) 0,8,12 weeks visual analog scale

Secondary

MeasureTime frame
Knee function 0,8,12 weeks Anterior knee pain scale,Femoral H-reflex 0,8,12 weeks The Nicolet EDX,Knee extensor isometric peak torque (Nm/kg) 0,8,12 weeks HUMAC NORM Isokinetic Dynamometer,Knee extensor, hip abductor and hip lateral rotator isokinetic peak torque (Nm/kg) 0,8,12 weeks HUMAC NORM Isokinetic Dynamometer,Central activation ratio 0,8,12 weeks HUMAC NORM Isokinetic Dynamometer

Countries

Thailand

Contacts

Public ContactSiraphat Prapobratanakul

Faculty of Medicine, Chulalongkorn University

6578322030@student.chula.ac.th022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026