Skip to content

Comparison of combined genicular nerve block and intra-articular steroid injection versus intra-articular steroid injection alone in knee osteoarthritis

Comparison of combined genicular nerve block and intra-articular steroid injection versus intra-articular steroid injection alone in knee osteoarthritis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260102005
Enrollment
52
Registered
2026-01-02
Start date
2026-01-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe osteoarthritis knee patients with chronic knee pain Knee osteoarthritis Genicular nerve block Intra-articular triamcinolone VAS score, WOMAC score, Knee ROM

Interventions

1) GNB : A mixture of 20 mg of Triamcinolone Acetonide (TA) and 1% lidocaine 6 ml was equally divided in three area injection under fluoroscope at the Orthopedic outpatient department 2)IACSI: 1 mL
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Genicular nerve block plus intra-articular triamcinolone,intra-articular triamcinolone alone

Sponsors

Faculty of Medicine Ramathibodi Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Age > 60 2.Confirm diagnosis OA knee with chronic knee pain 3.KL 3-4 4.Patient willing to participate in the study

Exclusion criteria

Exclusion criteria: 1.Previous knee surgery 2.Acute knee pain 3.Connective tissue disease affect knee joint 4.Suspected infection around knee 5.Previous peri-articular injection < 3 months 6.Drug allergy to local anesthetic or steroid 7.History of previous paresthesia and muscle weakness from other causes ex. Stroke ,spinal stenosis

Design outcomes

Primary

MeasureTime frame
VAS score 2,4,8,12 and 24 weeks Patient reported outcome using a questionnaire interview

Secondary

MeasureTime frame
WOMAC score 2,4,8,12 and 24 weeks measures pain, stiffness, and physical function of knee joint in daily activities using 22 self-administered questions scored, with higher scores indicating worse symptoms,Knee ROM 12 and 24 weeks Degree/Goniometer,All adverse events every time point All adverse events including numbness, paresthesia, motor weakness and post-injection flare

Countries

Thailand

Contacts

Public ContactChavarat Jarungvittayakon

Faculty of Medicine Ramathibodi Hospital, Mahidol University

J_chavarat@hotmail.com0903544915

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026