Primary Knee Osteoarthritis : Platelet rich plasma, activator, osteoarthritis
Conditions
Interventions
Injection of Mechanically Activated Platelet-Rich Plasma Injection in Knee Osteoarthritis,Injection of Non-Activated Platelet-Rich Plasma Injection in Knee Osteoarthritis
Experimental Drug,Experimental Drug
Mechanically Activated Platelet-Rich Plasma Injection in Knee Osteoarthritis,Non-activated Platelet-Rich Plasma Injection in Knee Osteoarthritis
Sponsors
Faculty of Medicine Vajira Hospital
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age over 50 years. 2.Diagnosed with Primary Knee Osteoarthritis. 3.Severity grade I to III according to the Kellgren-Lawrence Classification.
Exclusion criteria
Exclusion criteria: 1.History of prior surgery on the target knee. 2.History of fracture of the target knee. 3.Received injections or medications such as Glucosamine, Chondroitin, NSAIDs, or 4.Corticosteroids within the past 3 months. 5.Underlying diseases affecting platelet function (e.g., Thrombocytopenia) or current use of antiplatelet/anticoagulant medications (e.g., Aspirin, Clopidogrel). 6.Cognitive impairment or dementia that prevents understanding of the study or the ability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS) score 2, 4, 12, and 24 weeks Questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC score 2, 4, 12, and 24 weeks Questionnaire,Knee Osteoarthritis Outcome Score (KOOS) 2, 4, 12, and 24 weeks Questionnaire | — |
Countries
Thailand
Contacts
Public ContactKittitat Jaidee
Faculty of medicine, Vajira hospital
Outcome results
None listed