Myasthenia gravis who had involved ocular symtpoms (Ocular Myasthennia Gravis: OMG) Ocular myasthenia gravis
Conditions
Interventions
The patients were prescribed prednisolone less than 20 mg/day during the course of treatment.,The patients were prescribed prednisolone equal to or more than 20 mg/day during the course of treatment.
Treatment,Treatment
Low-dose prednisolone,Moderate-dose prednisolone
Sponsors
Chonburi hospital
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: The Myasthenic Gravis patients who had 1 unilateral or bilateral ptosis not attributable to eyelid pathology and demonstrating fatigability 2 diplopia due to extraocular muscle weakness not explained by isolated cranial nerve palsy 3 weakness of orbicularis oculi without neck muscle involvement 4 documented fatigability on sustained upward or lateral gaze for 30 to 60 seconds 5 a clinical diagnosis of ocular MG with initiation of standard therapy including pyridostigmine and prednisolone.
Exclusion criteria
Exclusion criteria: 1. incomplete clinical data 2. lost to follow-up 3. received prednisolone for conditions unrelated to MG.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respond to therapy 3 months 1.Complete remission 2.improve (Partial remission) 3. not improved. (Based on Neurologist decsion and MG-ADL score) | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactThippamas Pobsuk
Chonburi hospital
Outcome results
None listed