Individuals with Parkinsons disease experience tremors and impaired hand function PARKINSONS DISEASE, ACTION OBSERVATION THERAPY, ECCENTRIC EXERCISE, TREMORS, HAND FUNCTION, RANDOMIZED CONTROLLED TRIAL
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 50 and 80 years. 2. Clinically diagnosed with idiopathic PD at stages 2 to 3 according to the modified 3. Hoehn and Yahr scale (54). 4. Taking stable medication for at least one month prior to enrollment. 5. Mini-Mental Status Exam (MMSE) score > 24 (104). 6. Able to understand and follow verbal instructions.
Exclusion criteria
Exclusion criteria: 1. Clinically diagnosed with dementia or cognitive impairment. 2. Participation in a structured physical therapy program more than once per month. 3. A history of, or active diagnosis of, other neurological disorders such as stroke, idiopathic normal pressure hydrocephalus, or stiff person syndrome. 4. Presence of cardiopulmonary diseases that are not adequately controlled with medication, including but not limited to uncontrolled heart failure, severe chronic obstructive pulmonary disease (COPD), or unstable angina. 5. Musculoskeletal conditions that could interfere with study procedures, such as severe hand injury or recent fractures, or chronic neck pain that limits upper limbs mobility. 6. Current treatment with haemodialysis. 7. Uncontrolled hypertension, diabetes mellitus, or dyslipidaemia despite medical management.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tremor severity Baseline (Week 0) Post-intervention (Week 6) Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS),Inertial Measurement Units (IMUs) | — |
Secondary
| Measure | Time frame |
|---|---|
| Hand function Baseline (Week 0) Post-intervention (Week 6) Hand held dynamometer(HHD), Box and block test (BBT), Spiral test,Quality of life Baseline (Week 0) Post-intervention (Week 6) Parkinson's Disease Questionnaire (PDQ-39) | — |
Countries
Pakistan
Contacts
Faculty of Physical therapy Mahidol university Thailand