POST THORACOTOMY PATIENTS Post-surgical pain, Thoracotomy, Intensive Care Unit (ICU), Ketamine, Midazolam, Nalbuphine, Analgesia, Sedation, Randomized Controlled Trial, Postoperative complications, Dynamic compliance, Airway resistance, Post-thoracotomy, Opioid-sparing, Pain management, Postoperative care, Anesthesia, ICU sedation, Patient morbidity.
Conditions
Interventions
The intervention in this study involves comparing the effects of two analgesic-sedative regimens in post-thoracotomy ICU patients. Group A received a combination of ketamine (100mcg/kg/hr) and low-dos
Experimental Drug
KETAMINE WITH MIDAZOLAM
Sponsors
nill
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients planned for elective thoracotomy 2.Age between 30 to 70 years 3.Both genders 4.ASA grade less than or equal to III
Exclusion criteria
Exclusion criteria: 1.Patient refusal to participate 2.Known allergy or contraindication to the respective drugs 3.Pregnant women 4.BMI greater than 35 5.History of previous upper thoracic surgeries 6.Emergency surgery cases 7.Hemodynamic instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dynamic Compliance Baseline, 6 hours, 12 hours, 18 hours, 24 hours Dynamic compliance is measured by calculating the change in lung volume (tidal volume) for each change in pressure, using the formula: | — |
Secondary
| Measure | Time frame |
|---|---|
| Airway Resistance Baseline, 6 hours, 12 hours, 18 hours, 24 hours Airway resistance is calculated using the formula | — |
Countries
Pakistan
Contacts
Public ContactArooj Fatima
University of lahore
Outcome results
None listed