Hereditary breast cancer Breast cancer Genetic risk assessment Cancer genetic screening Hereditary breast cancer Genetic screening Genetic risk assessment BRCA mutation National Comprehensive Cancer Network NCCN criteria Implementation research Mixed methods study Thailand
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria * 1.Adult Thai patients diagnosed with breast cancer who received care at the study site during the study period. 2. Patients with available medical records sufficient for assessment using the NCCN genetic risk screening criteria. 3.Healthcare professionals involved in breast cancer care and genetic risk assessment. 4.Healthcare professionals who are eligible and willing to participate in the qualitative interview component of the study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria * 1. Patients with incomplete or missing medical records that prevent assessment using the NCCN genetic risk screening criteria. 2. Patients whose clinical data are unavailable or insufficient for retrospective review. 3. Patients who declined genetic evaluation or whose medical records could not be accessed for the quantitative component. 4. Healthcare professionals who are not directly involved in breast cancer care or genetic risk assessment. Healthcare professionals who are unwilling to participate in the qualitative interview process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perceptions of NCCN criteria implementation During study period after ethics approval In depth semi structured interviews with healthcare professionals analyzed using qualitative content analysis,Barriers to implementation of genetic risk screening During study period after ethics approval In depth semi structured interviews with healthcare professionals analyzed using qualitative content analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Facilitators of implementation of genetic risk screening During study period after ethics approval In depth semi structured interviews with healthcare professionals analyzed using qualitative content analysis,Proportion of patients screened for genetic risk During retrospective study period Review of medical records to determine the number and proportion of breast cancer patients assessed using the NCCN genetic risk screening criteria,Proportion of patients referred for genetic testing During retrospective study period Review of medical records to determine the number and proportion of breast cancer patients referred for genetic testing based on NCCN genetic risk screening criteria | — |
Countries
Thailand
Contacts
Mahidol University