The potential benefits of this combined approach in improving postoperative pain management update to ACL reconstruction. Ketorolac combined with Bupivacaine
Conditions
Interventions
Combination 0.25% bupivacaine with 60 mg ketorolac, total volume 20 ml applied to the hamstring donor site.,0.25% bupivacaine alone, total volume 20 ml applied to the hamstring donor site.
Experimental Drug,Active Comparator Drug
Group A,Group B
Sponsors
Nutcha Natetaweewat
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years 2. Diagnosed with anterior cruciate ligament (ACL) deficiency. 3. All patients underwent surgery between 2023 and 2025 at Maharaj Nakhon Ratchasima Hospital
Exclusion criteria
Exclusion criteria: 1. Allergies to NSAIDs or anesthetic agents 2. A history of renal failure or gastrointestinal bleeding 3. Pregnant 4. Significant knee pathologies such as collateral ligament or posterior cruciate ligament (PCL) injuries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain every 4 hours for 24 hours 10 mm Visual Analog Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first request for analgesic (T-rescue) with in 24 hr Time (min),VAS at T-rescue (10 scale) 24 hr 10 mm Visual Analog Scale (VAS) ,24 hrs morphine requirement (mg/kg) Discharge Measure before discharge ,Patient satisfaction Discharge Functional Measure before discharge,Hospital stay (days) Discharge Number Measure before discharge,Nausea vomiting Discharge Number Measure before discharge | — |
Countries
Thailand
Contacts
Public ContactNutcha Natetaweewat
Maharat Nakhon Ratchasima Building (Hospital )
Outcome results
None listed