non-linear nasal dorsum flat nasal tip thread lifting nose shaping
Conditions
Interventions
Multiple bidirectional Newton cog polydioxanone (PDO) threads will be used for nasal shaping and applied to both the nasal dorsum and columella. Local anesthesia will be administered prior to the proc
Experimental Device
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Participants aged 25 to 60 years, of both males and females. 2. Participants without indications for rhinoplasty, including those with a history of nasal trauma or congenital nasal deformities. 3. Participants with non linear nasal dorsum or a flat nasal tip, defined by drawing a reference line from the nasal tip through the lower lip to the chin, where the nasal tip lies below this imaginary line.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women 2. Participants with a history of prior nasal surgery. 3. Participants with underlying medical conditions, including platelet disorders, coagulation abnormalities, anemia, liver disease, malignancy, or autoimmune diseases. 4. Participants who smoke or have a history of heavy alcohol consumption. 5. Participants with dermatitis, open wounds, or skin infections in the nasal or intranasal area. 6. Participants with a history of allergy to local anesthetics, penicillins, or chloramphenicol. 7. Participants with a history of hormonal therapy, injectable or oral contraceptives, or regular use of NSAIDs. 8. Participants receiving medications that affect platelet function or blood coagulation, such as warfarin, direct oral anticoagulants (DOACs), or antiplatelet agents. 9. Participants who have received facial filler injections or botulinum toxin within 6 months prior to study enrollment. 10. Participants who have undergone facial lifting or tightening procedures within 6 months prior to study enrollment. 11. Participants with a history of keloid or hypertrophic scarring. 12. Participants with a psychiatric disorder diagnosed by a psychiatrist. 13. Participants who do not consent to facial photography for treatment evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Columella Labial Angle baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra,Columella height to Alar width ratio baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra,Nasofrontal Angle baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra,Nasomental Angle baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra,Tip projection ratio baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra,Nasofacial Angle baseline, immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Vectra | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score at treatment Visual analog scale,Safety immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Adverse event,Participants improvement scale immediate after treatment, 1 week, 1 month, 3 months, and 6 months post-treatment Quartile scale | — |
Countries
Thailand
Contacts
Public ContactThanya Techapichetvanich
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed