Effects and Underlying Mechanisms of Post-Exercise Ischemic Conditioning on Recovery from Fatigue Induced by High-Intensity Exercise

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251220011

Enrollment

Registered

2025-12-20

Start date

2025-12-31

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise-induced fatigue following high-intensity exercise (characterized by temporary declines in lower limb explosive power, muscle activation, and subjective recovery status) Blood Flow Restriction

Interventions

All subjects underwent graded cycle ergometer exercise to exhaustion for fatigue induction. BFR Group: Post-exercise, BFR band on proximal thigh (50mmHg above systolic BP), alternating left/right infl

Experimental Behavioral

Blood Flow Restriction (BFR)

Eligibility

Sex/Gender

Male

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1.Male college students majoring in physical education, aged 18-24 years. 2.No cardiovascular, metabolic diseases, history of deep vein thrombosis or limb vascular abnormalities confirmed by health screening. 3.Able to complete the prescribed high-intensity exercise, intervention and outcome measurement procedures. 4.Voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Subjects with BFR intervention contraindications (e.g., severe peripheral vascular disease, coagulation disorders). 2.Those with acute lower limb muscle injury, inflammation or pain that affects exercise or intervention. 3.Those with cognitive impairment or inability to cooperate with scales, EMG or fNIRS tests. 4.Those who have participated in similar intervention studies within 3 months. 5.Those who refuse to sign the informed consent form or cannot adhere to the study protocol.

Design outcomes

Primary

Measure	Time frame
Lower limb explosive power recovery Pre-exercise, immediately after exercise, immediately after intervention, 24 hours after intervention Countermovement Jump (CMJ) test to measure jump height; isokinetic muscle strength test to measure peak torque and total work	—

Secondary

Measure	Time frame
Surface electromyography indicators Pre-exercise, immediately after exercise, immediately after intervention Recorded by surface electromyography instrument	—

Countries

China

Contacts

Public ContactQi Cheng

Hebei Normal University

1476665124@qq.com13288790903

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026