Carpal tunnel syndrome this study is to compare the clinical efficacy and safety of ultrasound-guided pulsed radiofrequency and hyaluronidase hydrodissection in the treatment of carpal tunnel syndrome. This research seeks to evaluate both techniques in terms of pain relief, functional improvement, nerve conduction parameters, and potential complications, in order to identify the more effective minimally invasive approach for managing carpal tunnel syndrome.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adults aged from 20 to 80 years 2. Clinical diagnosis of CTS with symptoms for at least 3 months 3. Electrophysiological evidence of mild to moderate CTS 4. No previous intervention for CTS in the affected hand
Exclusion criteria
Exclusion criteria: 1. Previous wrist surgery or trauma 2. Medical history of polyneuropathy, thoracic outlet syndrome, or brachial plexopathy 3. Coagulopathy or local infection at injection site 4. Pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset time of significant pain relief 1 month VAS measures pain on a 10-cm line from 0 (no pain) to 10 (worst pain). The patient marks the line, and the distance from the start point is recorded as the pain score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) 1weeks and 1-, 3-, and 6-months post-injection BCTQ is measured using two scores the Symptom Severity Scale and the Functional Status Scale. Patients rate symptoms and hand function each item is scored from 1 to 5, and mean scores are calculated.,Cross-sectional area (CSA) baseline and then at 1-, 3-, and 6-months post-injection CSA is measured by ultrasound at the carpal tunnel inlet the median nerve area is traced inside the hyperechoic rim, and the value is recorded.,Sensory nerve conduction velocity (SNCV) baseline and 1, 3, and 6months post-injection SNCV is measured by stimulating a sensory nerve and recording the response. Velocity in meters per second equals distance between electrodes divided by response latency. | — |
Countries
Egypt
Contacts
Sohag university