Women with positive HPV DNA testing at Maharat Nakorn Chiangmai hospital HPV, vaginal dysbiosis
Conditions
Interventions
Apply 1 amplue (5 mg) vaginal supposity per day hs and 7 day per months
Total 6 months,No treatment
Experimental Drug,No Intervention No treatment
Intravaginal lactic acid and glycogen containing gel products,Control
Sponsors
Faculty of medicine, Chiangmai University
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Women aged 35 to 65 years 2.Patients who are being followed up due to previous abnormal results or newly referred patients whose HPV DNA test and cytology indicate HPV infection according to any of the following criteria 2.1. Positive for HPV types 16/18, regardless of cytology results and colposcopic direct biopsy shows no CIN2 or higher severity 2.2.Positive for non16/18 HPV types with abnormal cytology and colposcopic direct biopsy shows no CIN2 or higher severity 2.3. Positive for other HPV types (non-16/18) with normal cytology 3. Willing to refrain from using any intravaginal products (e.g., probiotics or vaginal cleansers) during the study. 4. Able to provide written informed consent and comply with study procedures.
Exclusion criteria
Exclusion criteria: 1.Pregnant women 2.Immunocompromised status or receiving immunosuppressive therapy 3.Colposcopic directed biopsy showing CIN2 or higher 4.History of hysterectomy 5.Allergy to any component of the study product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV test in 6 months 6 months Co-testing | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytology 6 months Liquid based cytology,Vaginal pH 6 months Universal indicator pH paper | — |
Countries
Thailand
Contacts
Public ContactPhitsinee Sabyeying
Faculty of Medicine, Chiang Mai University
Outcome results
None listed