Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentine Caries in Children

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251215003

Enrollment

260

Registered

2025-12-15

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries Control Dental Caries, Sodium Fluoride (NaF), Silver Diamine Fluoride (SDF)

Interventions

To evaluate the efficacy of Sodium Fluoride preventing caries and promoting remineralization process. ,To evaluate the efficacy of Silver Diamine Fluoride preventing caries and promoting remineralizat

Experimental Drug,Experimental Drug

Sodium Fluoride (NaF),Silver Diamine Fluoride

Eligibility

Sex/Gender

All

Age

3 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. Children having at least one active dentine carious lesion in a deciduous tooth . 2. Teeth that were restorable and free from pulpal involvement. 3. Cooperative children capable of tolerating simple clinical examination and topical application.

Exclusion criteria

Exclusion criteria: 1. A history of systemic illness or long-term medication. 2. Known allergy to fluoride, silver, or colophony-based agents. 3. Presence of deep carious lesions with pulpal involvement or abscess.

Design outcomes

Primary

Measure	Time frame
Caries Prevention 6 months Visual-tactile examination	—

Secondary

Measure	Time frame
Oral Hygiene status 6 months Visible Plaque Index	—

Countries

Pakistan

Contacts

Public ContactVinessa Gill

Fatima Jinnah Dental College

vanessagill176@gmail.com345303315

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026