Hypertension blood pressure, concurrent training, arterial stiffness, protein supplementation, inflammation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adults with hypertension (SBP greater than or equal to130 mmHg or DBP greater than or equal to80 mmHg ) 2.Age 35-59 years 3.Body mass index greater than or equal to 23 kg per m2 4.Sedentary lifestyle 5.Stable antihypertensive medication use (if any) for greater than or equal to 3 months 6.No participation in supervised exercise or nutrition programs in the preceding 3 months 7.Able and willing to comply with study procedures, supplementation, and exercise sessions 8.Provided written informed consent
Exclusion criteria
Exclusion criteria: 1.Current smoking 2.History of type 2 diabetes, coronary artery disease, peripheral vascular disease, or stroke 3. Uncontrolled hypertension 4.Musculoskeletal disorders limiting moderate-intensity exercise 5.Psychiatric or cognitive conditions that may compromise adherence 6.Clinically significant renal, hepatic, or hematologic disease. 7.Use of glucose-lowering agents, anti-inflammatory drugs, or dietary supplements known to influence vascular or metabolic function 8.Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure before and after 8 weeks of the intervention automatic oscillometric sphygmomanometer ,Arterial stiffness before and after 8 weeks of the intervention baPWV (BP-203RPE III, Omron Colin, Japan) | — |
Secondary
| Measure | Time frame |
|---|---|
| hs-CRP before and after 8 weeks of the intervention immunoturbidimetric assay,CBC-derived indices before and after 8 weeks of the intervention automated hematology analyzer ,Electrolytes before and after 8 weeks of the intervention ion-selective electrode method,Blood chemistry before and after 8 weeks of the intervention automated analyzer,Atherogenic indices before and after 8 weeks of the intervention calculation form lipid profiles,Anthropometry and Body Composition before and after 8 weeks of the intervention circumference and BIA-derived,Cardiorespiratory Fitness before and after 8 weeks of the intervention graded exercise test on cycle ergometer with breath-by-breath gas analysis,Muscular Endurance before and after 8 weeks of the intervention Push-up test and Wall sit test | — |
Countries
Thailand
Contacts
Faculty of Sports and Health Science, Kasetsart University