The Efficacy of Thai herbel Thepchit in Patients with Co-Morbid Insomnia and Obstructive Sleep Apnea Using Continuous Positive Airway Pressure: A Double-Blind Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251209012

Enrollment

Registered

2025-12-09

Start date

2025-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COMISA Obstructive sleep apnea INSOMNIA COMISA Obstructive sleep apnea Herb

Interventions

350 mg per capsule intake 4 capsule before bedtime,350 mg capsule placebo with make scents and color same as herbal capsule

Experimental Drug,Placebo Comparator Drug

herbal,placebo

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: OSA on PAP therapy (diagnosed by ICSD-3-TR) with insomnia(diagnosed by ICSD-3-TR with ISI index more than 15)

Exclusion criteria

Exclusion criteria: renal and hepatic disease on anticoagulant and antiplatelet history of herb allergy

Design outcomes

Primary

Measure	Time frame
Thai-ISI score 2 year Satisfaction score by questionaire/Chi-square test	—

Secondary

Measure	Time frame
The Epworth Sleepiness Scale: Thai version 2 year Satisfaction score/Time point	—

Countries

Thailand

Contacts

Public ContactNavarat Kasemsuk

Faculty of medicine Siriraj hospital, Mahidol university

mintkus32@hotmail.com0870890444

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026