Effects of dynamic standing on motor-cognitive function in people with cognitive prefrailty and mild cognitive impairment: Three-arm randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251208004

Enrollment

Registered

2025-12-08

Start date

2026-03-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly with prefrailty and mild cognitive impairment Balance, Cognitive Impairment, Elderly, Frailty, Rehabilitation

Interventions

Participants will receive cognitive training on standing desk with balance pad 40 min/session, total 12 sessions,Participants will receive cognitive training on standing desk 40 min/session, total 12

Experimental Other,Active Comparator Other,Active Comparator Other

Dynamic standing group,Static standing group,Seated training group

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age more than or equal 65 years old 2.Prefrailty, defined by Fried frailty phenotype, requires meeting 2 out of 5 criteria (shrinking, weakness, slowness, exhaustion, low activity level) 3.Have mild cognitive impairment 4.Who are able to stand at least accumulative 40 min per day 5.Willing to join research

Exclusion criteria

Exclusion criteria: 1.Inability to stand or walk without gait aids 2.Musculoskeletal problems interfere with standing 3.Has history of joint replacement (hip, knee) within 6 months 4.Neurological diseases (stroke, PD, TBI, MS, etc.) 5.Diagnosed with dementia, Alzheimer disease and Alzheimer disease related disorder 6.Unstable medical conditions 7.Participate in other research about exercise activities or cognitive training

Design outcomes

Primary

Measure	Time frame
motor cognitive task baseline, post-intervention Dual timed up and go	—

Secondary

Measure	Time frame
reaction time baseline, post-intervention choice stepping reaction time,balance assessment baseline, post-intervention Limits of stability, and o Modified Clinical Test of Sensory Interaction on Balance ,muscle strength baseline, post-intervention knee extensors strength test ,functional tests baseline, post-intervention five time sit to stand, 4 meters gait speed ,fear of fall baseline, post-intervention Short Falls Efficacy Scale International,musculoskeletal discomfort average total 12 sessions visual analogue scale,cognitive tests baseline, post-intervention digit span, trail making test, inhibitory control, simple reaction time	—

Measure

Time frame

reaction time baseline, post-intervention choice stepping reaction time,balance assessment baseline, post-intervention Limits of stability, and o Modified Clinical Test of Sensory Interaction on Balance ,muscle strength baseline, post-intervention knee extensors strength test ,functional tests baseline, post-intervention five time sit to stand, 4 meters gait speed ,fear of fall baseline, post-intervention Short Falls Efficacy Scale International,musculoskeletal discomfort average total 12 sessions visual analogue scale,cognitive tests baseline, post-intervention digit span, trail making test, inhibitory control, simple reaction time

—

Countries

Thailand

Contacts

Public ContactChernkhuan Stonsaovapak

Chulalongkorn University

chernkhuan@gmail.com022564433

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026