Comparing the Analgesic Efficacy of Ultrasound-Guided Bilateral Modified Thoracolumbar Interfacial Plane Block in Patients Undergoing Oblique Lateral Interbody Fusion with Posterior Screw Fixation : A Randomized Controlled Trial

Comparing the Analgesic Efficacy of Ultrasound-Guided Bilateral Modified Thoracolumbar Interfacial Plane Block in Patients Undergoing Oblique Lateral Interbody Fusion with Posterior Screw Fixation: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251208002

Enrollment

Registered

2025-12-08

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Undergoing Oblique Lateral Interbody Fusion with Posterior Screw Fixation mTLIP block, OLIF surgery, Modified Thoracolumbar Interfascial Plane Block, OLIF with PPS

Interventions

Bilateral Modified Thoracolumbar Interfacial Plane Block with Normal saline injection,Bilateral Modified Thoracolumbar Interfacial Plane Block with 0.25 % bupivacaine 20 ml each sides

Sham Comparator Drug,Experimental Drug

Control group,mTLIP group

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patient who was scheduled for Oblique Lateral Interbody Fusion with Posterior Screw Fixation 1-2 levels at King Chulalongkorn Memorial Hospital ASA physical status Class I-II

Exclusion criteria

Exclusion criteria: - Allergy to amide - Allergy to multimodal analgesia protocol - Coagulopathy - body mass index > 40 kg/m2 - skin infection - Chronic opioid used - Inability to follow command

Design outcomes

Primary

Measure	Time frame
Morphine consumption in PACU 1 hr post operative milligrams	—

Secondary

Measure	Time frame
Back pain score at rest and during movement Preoperative, Postoperative at 0, 1, 2, 6, 12, 24, 48 hours, 2 week, 1 month, 3 month Numerical rating scale,Leg pain score at rest and during movement Preoperative, Postoperative at 0, 1, 2, 6, 12, 24, 48 hours, 2 week, 1 month, 3 month Numerical rating scale,Cumulative opioid consumption during admission During admission Milligrams,Time to first rescue analgesia During admission Hour,Total intraoperative fentanyl consumption Intraoperative period Micrograms,Postoperative early ambulation 24 hrs Hour,Pain memory recall score 24 and 72 hours Numerical rating scale,Duration of admission During admission Hours,Satisfaction score 72 hrs post op 1-10 points,Functional assessment Preop, 1 month and 3 month post op ODI, EQ-5D-5L,Complication: Nausea vomitting, dizziness, sleep disturbance Preop, 24, 48, 72 hrs post op Likert scale	—

Measure

Time frame

Back pain score at rest and during movement Preoperative, Postoperative at 0, 1, 2, 6, 12, 24, 48 hours, 2 week, 1 month, 3 month Numerical rating scale,Leg pain score at rest and during movement Preoperative, Postoperative at 0, 1, 2, 6, 12, 24, 48 hours, 2 week, 1 month, 3 month Numerical rating scale,Cumulative opioid consumption during admission During admission Milligrams,Time to first rescue analgesia During admission Hour,Total intraoperative fentanyl consumption Intraoperative period Micrograms,Postoperative early ambulation 24 hrs Hour,Pain memory recall score 24 and 72 hours Numerical rating scale,Duration of admission During admission Hours,Satisfaction score 72 hrs post op 1-10 points,Functional assessment Preop, 1 month and 3 month post op ODI, EQ-5D-5L,Complication: Nausea vomitting, dizziness, sleep disturbance Preop, 24, 48, 72 hrs post op Likert scale

—

Countries

Thailand

Contacts

Public ContactWirinaree Kampitak

King Chulalongkorn Memorial Hospital

nutong127@yahoo.com0899955666

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026