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Comparison of Gluma, Er,Cr:YSGG laser, and combination therapy for reducing tooth sensitivity after non-surgical periodontal treatment

Chemical and Laser Desensitization Approaches for Managing Dentin Hypersensitivity After Non-Surgical Periodontal Therapy: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20251202006
Enrollment
52
Registered
2025-12-02
Start date
2025-04-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin hypersensitivity that develops after non-surgical periodontal treatment, Periodontitis Root Planing, Dentin Sensitivity, Lasers, Periodontitis

Interventions

Participants receive Gluma Desensitizer applied directly to hypersensitive cervical surfaces for 60 seconds using a microbrush. The tooth surface is gently air dried until the material loses its gloss
Gluma,Laser,Combination

Sponsors

Ece Acikgoz Alparslan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adults aged nineteen years or older 2. Diagnosis of Stage III or Stage IV periodontitis according to the 2017 World Workshop criteria 3. Presence of at least twenty permanent teeth 4. Non surgical periodontal treatment performed prior to enrollment 5. Development of dentin hypersensitivity after periodontal treatment 6. Visual Analog Scale score greater than four 7. Schiff Cold Air Sensitivity Scale score of two or three 8. No desensitizing treatment or desensitizing toothpaste use before the study 9. Ability to attend clinical follow up visits for six months 10. Participant willing to sign written informed consent and comply with study procedures

Exclusion criteria

Exclusion criteria: 1. Use of antibiotics or analgesic medication within the last six months 2. Smoking ten or more cigarettes per day 3. Pregnancy or breastfeeding 4. History of periodontal therapy in the previous six months 5. Existing dentin hypersensitivity prior to periodontal treatment 6. Use of desensitizing toothpaste or sensitivity treatment before enrollment 7. Presence of tooth cracks erosion abrasion or other structural defects 8. Parafunctional habits including bruxism or clenching 9. Allergy or adverse reaction to Gluma components including glutaraldehyde or hydroxyethyl methacrylate 10. Contraindications to laser use including cardiovascular respiratory bleeding or immune conditions 11. Systemic disease or medical condition that could influence pain perception or study outcomes 12. Inability to complete the six month follow up schedule

Design outcomes

Primary

MeasureTime frame
Change in dentin hypersensitivity Baseline, Post treatment, 1week, 2weeks, 1month, 2months, 6months Visual Analog Scale,Change in dentin hypersensitivity Baseline, Post treatment, 1week, 2weeks, 1month, 2months, 6months Schiff Sensitivity Scale

Secondary

MeasureTime frame
Adverse events monitoring At all follow up visits Clinical examination and patient reporting,Recurrence or need for retreatment 6months Clinical reassessment of sensitivity return

Countries

Turkey

Contacts

Public ContactEce Acikgoz Alparslan

Trakya University

eceacikgoz@trakya.edu.tr2842364551

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026