Effect of increasing eccentric time under tension on one repetition maximum in resistant exercise

Effect of increasing eccentric time under tension (TUT) on one repetition maximum (1 RM) in resistant exercise of knee extensor muscles: single-blinded randomized controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251201008

Enrollment

Registered

2025-12-01

Start date

2024-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults aged 25 to 50 years without regular exercise habits, to investigate muscle strengthening and functional performance of knee extensors through eccentric resistance training Eccentric training

Interventions

resistance exercise of knee extensors with 5 second in eccentric contraction ,resistance exercise of knee extensors with 2 second in eccentric contraction

Experimental Behavioral,Experimental Behavioral

Eccentric time under tension resistance training (5 second eccentric phase),Conventional resistance training (2 second eccentric phase)

Eligibility

Sex/Gender

All

Age

25 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 25 to 50 years. 2. Able to stand, walk, and sit independently during testing. 3. Participants who understand and provide informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Individuals who have participated in regular resistance exercise training continuously during the past 1 year prior to the study. 2. Individuals who have experienced knee pain within 1 month prior to participation. 3. Individuals with any conditions affecting exercise performance, including: 3.1. Neuromuscular or musculoskeletal disorders such as multiple sclerosis, rheumatoid arthritis, or peripheral neuropathy. 3.2. History of any type of cancer. 3.3. Peripheral vascular diseases such as deep vein thrombosis. 3.4. Chest pain at rest or during exercise. 3.5. History of myocardial infarction or stroke. 4. Individuals with contraindications to exercise according to the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) guidelines. 5. Individuals taking medications that may cause dizziness during exercise, such as anticonvulsants, antidepressants, antipsychotics, anxiolytics, or antihistamines.

Design outcomes

Primary

Measure	Time frame
1RM isotonic knee extension at 4 weeks after end of the intervention Baechle and Earle (2008) formula	—

Secondary

Measure	Time frame
30 second chair stand test, Post exercise RPE at 4 weeks after end of the intervention, after every post exercise session 30 second chair stand test, Borg scale	—

Countries

Thailand

Contacts

Public ContactPawee Juengjanya

Department of Rehabilitation Medicine, Maharat Nakhon Ratchasima Hospital

pawin_n@icloud.com0990748222

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026