Internal jugular vein distensibility index versus changes in end-tidal CO2 to predict fluid responsiveness in mechanically ventilated patients with shock.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251129004

Enrollment

Registered

2025-11-29

Start date

2024-08-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated pateints with shock Shock Internal jugular vein distentsibility index End tidal CO2 Fluid responsiveness Shock

Interventions

Experimental Device

IJVDi and ETCO2

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adult (>18 years old) 2. Mechanically ventilated patients with shock (controlled ventilation; Richmond agitation sedation scale (RASS) less than -3 (moderate sedation)) with tidal volume >/= 8 ml / kg predicted body weight

Exclusion criteria

Exclusion criteria: 1. IJV thrombosis/obstruction/stenosis 2. History of irradiation or surgery of the neck region 3. Atrial fibrillation 4. Significant valvular heart disease 5. Left ventricular assisted device 6. Pregnancy 7. Previous volume expander greater than 4 liters

Design outcomes

Primary

Measure	Time frame
Cut point point At intervention IJVDi, ETCO2 change	—

Secondary

Measure	Time frame
Sensitivity At intervention IJVDi, ETCO2 change,Specificity At intervention IJVDi, ETCO2 change,ROC At intervention IJVDi, ETCO2 change	—

Countries

Thailand

Contacts

Public ContactTRIRONG CHOOSONGDET

Chulalongkorn university

memorizer.dx@gmail.com0944969865

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026