Children with moderate to severe allergic rhinitis children Allergic rhinitis Vitamin D
Conditions
Interventions
Children with low vitamin D level (25-OHD level below 20 ng/ml) will receive a loading dose of vitamin D then vitamin D supplement for total course 8weeks ,Children with low vitamin D level (25-OHD le
Experimental Drug,Placebo Comparator Drug,Experimental Drug,Placebo Comparator Drug
Sponsors
Mahidol university
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 5-18 years old with moderate to severe allergic rhinitis
Exclusion criteria
Exclusion criteria: 1.Serum 25-(OH)D level less than 10 ng/ml with clinical ricket 2. Patient with associated nasal comorbidities 3. Patient with associated systemic comorbidities affecting 25-(OH)D level 4. Individuals who have received medications affecting 25-(OH)D level.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical improvement of allergic rhinitis 8 weeks visual analog scale,clinical improvement of allergic rhinitis 8 weeks Total nasal symptom score,clinical improvement of allergic rhinitis 8 weeks peak nasal inspiratory flow | — |
Secondary
| Measure | Time frame |
|---|---|
| prevalence of vitamin D deficiency in allergic rhinitis children At the start of study 25-OHD level,correlation between serum 25-(OH)D level and rhinitis symptom severity At the start of study 25-OHD level, total nasal symptom score, visual analog scale, peak nasal inspratory flow | — |
Countries
Thailand
Contacts
Public ContactNatwalee Thongnoi
Mahidol university
Outcome results
None listed