Melatonin in Neurosensory Recovery after Orofacial Cyst Surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251127006

Enrollment

Registered

2025-11-27

Start date

2025-04-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orofacial cysts requiring surgical management (enucleation/marsupialization) with postoperative neurosensory impairmen melatonin, neurosensory recovery, inferior alveolar nerve, orofacial cysts, oral surgery

Interventions

Melatonin 10 mg orally at night, 1 day before surgery, continued for 21 days + standard care,Standard postoperative care only

Experimental Drug,Active Comparator No treatment

melatonin group ,non melatonin group

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: cysts near IAN/lingual/mental nerve

Exclusion criteria

Exclusion criteria: Pre-existing deficits neurological/systemic disease, neurotropic/antioxidant meds pregnant/lactating

Design outcomes

Primary

Measure	Time frame
Neurosensory recovery (two-point discrimination) 1,3 & 6 months pin prick test, two point discrimination	—

Secondary

Measure	Time frame
Patient-reported symptoms 1,3 & 6 months Visual Analogue Scale (VAS)	—

Countries

India

Contacts

Public ContactPIYUSH DALMIA

Bapuji Dental College and Hospital Karnataka

piyush.dalmia25@gmail.com07008841412

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026