Prostate cancer Hypofractionated and conventional radiation therapy in Prostate cancer.
Conditions
Interventions
Hypofractionated radiotherapy 60gray/20fractions for 4 weeks treatment duration.,Conventional radiotherapy 70gray/35fractions for 7 weeks treatment duration.
Hypofractionated radiotherapy[ 60gray/fractions],Conventional radiotherapy[70gray/fractions]
Sponsors
Sohag University Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1-Patients with prostatic adenocarcinoma. 2-patients aged 18-80 years old. 3-no other malignancy. 4-patients with intermediate ,high and very high risk stratifications. 5- patients with performance status 0-1.
Exclusion criteria
Exclusion criteria: 1-Patients with metastatic disease. 2-poor performance status. 3-patients younger than 18 years and more than 80 years. 4-patients with contraindications for radiotherapy. 5-Histological type other than adenocarcinoma. 6-Patients with significant comorbidities might affect treatment completion and follow up. 7-Presence of other malignancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute toxicity 90 days post radiation RTOG acute morbidity scoring criteria | — |
Secondary
| Measure | Time frame |
|---|---|
| Local control every 3months after radiotherapy PSA level and MRI prostate,biochemical free survival 1 year post radiation PSA level | — |
Countries
Egypt
Contacts
Public ContactSamah Ahmed
Sohag University Hospital
Outcome results
None listed