Erector Spinae Plane Block with Dexamethasone versus Standard Care for Postoperative Analgesia after Lumbar Spinal Fusion: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251124016

Enrollment

Registered

2025-11-24

Start date

2024-06-07

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain following posterior lumbar spinal fusion in adult patients Erector Spinae Plane Block, Dexamethasone, Posterior Lumbar Interbody Fusion, Postoperative Pain, Area Under the Curve of Visual Analog Scale, Morphine Consumption.

Interventions

- Patients in the ED group received intravenous dexamethasone (8 mg). The ESPB was performed after wound closure with the patient in the prone position. - Paracetamol 1 g IV every 8 h - Ketorolac 30

Experimental Procedure/Surgery,No Intervention Other

ESPB combine dexamethasone (ED),control

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1. ASA physical status I - II 2. Patients who were scheduled to undergo elective posterior lumbar spinal fusion under general anesthesia were screened. 3. Patients who provided written informed consent were enrolled in the study.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Pregnant patients 3. Allergy to any of the study medications 4. Complications related to surgery or anesthesia: neurological or cognitive disorders, coagulopathy, or infection at the injection site.

Design outcomes

Primary

Measure	Time frame
Pain Intensity 24 hours after surgery of receiving the intervention Visual Analog Scale,Total Morphine Consumption 24 hours after surgery of receiving the intervention Total morphine (mg) consumption all doses administered via intravenous patient-controlled analgesia (IV - PCA) and rescue boluses	—

Secondary

Measure	Time frame
Incidence of Opioid-Related Adverse Events and ESPB-Related Complications 24 hours after surgery of receiving the intervention Incidence of opioid-related side effects: nausea, vomiting, pruritus, respiratory depression, ESPB-related complications (bleeding, infection, or local anesthetic systemic toxicity),Quality of Recovery 24 hours after surgery of receiving the intervention the validated 15-item Quality of Recovery (QoR-15) questionnaire	—

Measure

Time frame

Incidence of Opioid-Related Adverse Events and ESPB-Related Complications 24 hours after surgery of receiving the intervention Incidence of opioid-related side effects: nausea, vomiting, pruritus, respiratory depression, ESPB-related complications (bleeding, infection, or local anesthetic systemic toxicity),Quality of Recovery 24 hours after surgery of receiving the intervention the validated 15-item Quality of Recovery (QoR-15) questionnaire

—

Countries

Vietnam

Contacts

Public ContactMinh Nguyen

Hue Univercity

nvminh.gmhs@huemed-univ.edu.vn84914145075

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026