FindTrial
Sign In

The effects of SPEAK OUT voice therapy in Parkinson's disease

Comparison of the effects of SPEAK OUT voice therapy on improving swallowing difficulties in advanced Parkinson's disease patients who have undergone deep brain stimulation surgery versus those receiving medical therapy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20251108001
Enrollment
48
Registered
2025-11-08
Start date
2025-05-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced PD with disease duration more than 10 years, age 45 to 85 years Hoehn and Yahr stage 3-5 complaint of difficulty swallowing with SDQ 1 to 10 Parkinson disease, Voice therapy, Speech therapy, Swallowing, Dysphagia

Interventions

advanced PD patients treated with medication who received SPEAK OUT voice therapy for 8 weeks. Participants in the intervention groups (medication and DBS) received 12 sessions of SPEAK OUT voice ther
Experimental Other,Experimental Other
Medication,DBS (Deep brain stimulation)

Sponsors

Faculty of Medicine, Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. advanced PD with disease duration more than 10 years 2. age 45 to 85 years 3. Hoehn and Yahr stage 3 to 5 4. complaint of difficulty swallowing with SDQ 1 to 10 5. stable PD symptoms for more than 3 months 6. normal hearing according to Rinne and Weber tests and 7. commitment to practicing voice therapy daily for 8 weeks

Exclusion criteria

Exclusion criteria: (1) had other neurological damage or diseases causing swallowing disorders; (2) scored less than 19 points on the Thai Mental State Examination (TMSE); (3) had laryngeal surgery or pathology; (4) had head or neck cancer; (5) had severe temporomandibular joint disorder; or (6) were pregnant

Design outcomes

Primary

MeasureTime frame
Swallowing symptoms within one month after the intervention Swallowing Disturbance Questionnaire (SDQ) scores—

Secondary

MeasureTime frame
tongue muscle strength within one month after the intervention Lingual manual muscle strength testing , dysphagia severity and quality of life within one month after the intervention Thai version of the MD Anderson Dysphagia Inventory (MDADI-TH),the quality of life in patients with Parkinson disease within one month after the intervention The Parkinson Disease Questionnaire8 (Thai PDQ8), voice intensity (dB) within one month after the intervention voice intensity (dB) recorded by ZOOM H4N Pro voice recorder ,maximum phonation time (MPT) within one month after the intervention maximum phonation time (MPT) recorded by ZOOM H4N Pro voice recorder,Cepstral Peak Prominence (CPP) within one month after the intervention Cepstral Peak Prominence (CPP) calculated by praat,formant frequency within one month after the intervention formant frequency calculated by praat,impact of voice problems on quality of life within one month after the intervention Voice Handicap Index (VHI) questionnaire—

Countries

Thailand

Contacts

Public ContactNontakorn Likhitwitayawuid

Chulalongkorn University Hospital

nontakorn.lik@gmail.com028496600

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026