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Effect of Modic changes on fusion rate in Lumbar interbody fusion surgery. Ambidirectional cohort study

Effect of Modic changes on fusion rate in Lumbar interbody fusion surgery. Ambidirectional cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20251107002
Enrollment
172
Registered
2025-11-07
Start date
2025-08-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Modic change Modic change fusion rate fusion spinal fusion interbody fusion surgical site infection pain EQ5D5L ODI VAS pain

Interventions

patients without modic change in preoperative MRI at fusion level,patients with modic change in preoperative MRI at fusion level
Other,Other
patients without modic change,patients with modic change

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who underwent a single-level Lumbar Interbody Fusion surgery.

Exclusion criteria

Exclusion criteria: 1. Patients who have undergone surgery due to a spinal tumor. 2. Patients with a history of previous lumbar/lumbosacral spine surgery. 3. Patients with a history of injury to the lumbar/lumbosacral spine. 4. Patients with a history of a spinal tumor. 5. Patients who have been followed up for less than one year.

Design outcomes

Primary

MeasureTime frame
fusion rate post LIF at day 0, 3 months, 6 months, 1 year Bridwell grading

Secondary

MeasureTime frame
Patient reported outcomes post LIF at day 0, 3 months, 6 months, 1 year VAS, ODI, EQ5D5L,surgical site infection post LIF at day 0, 3 months, 6 months, 1 year percent

Countries

Thailand

Contacts

Public ContactWerasak Sutipornpalangkul

Faculty of medicine, Siriraj hospital, Mahidol university

tewsvja@gmail.com024197965

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026