Microscopic and Visual Analysis of White Spot Lesion Prevention Using Opal seal and Transbond XT Primers: A split mouth study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251102005

Enrollment

Registered

2025-11-02

Start date

2020-02-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White spot lesion Demineralization of enamel Dental Caries Fluoride Demineralization Primers

Interventions

A light-cured sealant known as Opalseal (OS) (Ultradent, Salt Lake City, UT) is available contains 38% glass ionomer particles combined with nanofillers and is designed to be rechargeable, enhancing i

Experimental Other,Active Comparator Other

Opal seal,Transbond XT primer

Eligibility

Sex/Gender

All

Age

15 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. No visible enamel demineralization 2. No restorations on buccal surface of teeth 3. No enamel hypoplasia or any morphology of tooth 4. Presence of only permanent teeth

Exclusion criteria

Exclusion criteria: 1. Physically or mentally challenged 2. Under chronic medication 3. Suffering from any systemic condition which directly or indirectly influence the study outcome 4. Pregnant or lactating mothers

Design outcomes

Primary

Measure	Time frame
White spot lesion 16 October 2020 to 19 January 2021 Visual and microscopic evaluation	—

Secondary

Measure	Time frame
Depth of demineralized enamel 5 April 2021 to 1 February 2023 Assessed using polarized light microscope	—

Countries

India

Contacts

Public ContactKiran P

Rajiv Gandhi University of Health Sciences

kirankumarp2880@gmail.com9854601557

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026