elderly patients undergoing hip fracture surgery multimodal analgesia visual analog scale morphine consumption cumulated ambulation score early ambulation
Conditions
Interventions
Extended group received three doses of intravenous dexamethasone preoperatively, and 24 hours and 48 hours after the first dose. ,Standard group received two doses of intravenous dexamethasone preoper
Extended group,Standard group
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. closed fracture of the femoral neck or pertrochanteric region of the femur 2. age 60 years or older 3. scheduled for bipolar hemiarthroplasty or closed reduction and internal fixation with proximal femoral nail anti-rotation 4. underwent surgical intervention within 7 days following the diagnosis of hip fracture 5. preinjury independent ambulatory status without gait aids 6. willing to follow the study protocol and given their consents
Exclusion criteria
Exclusion criteria: 1. multiple trauma or fractures 2. had a previous hip fracture or surgery 3. had an underlying neuromuscular disorder or cognitive impairment that affected muscle function or made them unable to follow the postoperative protocol 4. had a pathologic fracture other than osteoporosis such as a metastatic fracture 5. had a contraindication or allergy to dexamethasone 6. diagnosed with diabetes mellitus and had HbA1c > 7.5% 7. were unable to follow the postoperative protocol 8. who wanted to withdraw by themselves.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain at rest and during motion 0-72 hours after surgery 10-point visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphine consumptin 0-3 days after surgery mg,Blood sugar 0-3 days after surgery amount of morphine used,C-reactive protein 0-3 days after surgery blood test,Creatinine kinase 0-3 days after surgery blood test,Cumulated Ambulation Score 0-3 days after surgery performance-based scale,Barthel Index 0-24 weeks after surgery questionnaire,Harris Hip Score 0-24 weeks questionnaire,EQ-5D-5L 0-24 weeks questionnaire | — |
Countries
Thailand
Contacts
Public ContactPaphon Sangasoongsong
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed