Patients with otomycosis Otomycosis
Conditions
Interventions
Applying 2% Acetic acid to the ear canal by the investigator, coating all areas of the canal up to the tympanic membrane on day0, 3, 7, 14,1%Clotrimazole ear drops 4 drops into affected ear 3 times da
Experimental Drug,Active Comparator Drug
Topical 2% Acetic Acid,1% Clotrimazole Ear drops
Sponsors
Faculty of Medicine, Khon Kaen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years 2. Patients diagnosed with Otomycosis(from symptoms and physical examination) 3. Patient who agrees to participate in the study after receiving a full explanation of the research details and signing the informed consent form
Exclusion criteria
Exclusion criteria: 1. Patients with perforated tympanic membrane/chronic otitis media 2. Patients with a history of Canal wall down mastoidectomy 3. Patients with a history of allergy to topical ear drops medication 4. Patients with a history of treatment otomycosis within the past 3 months 5. Patients with severe symptoms of otomycosis, with marked swelling of the external auditory canal obscuring more than half of tympanic membrane
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of Otomycosis 3 days, 7 days, 14 days Evaluated by research advisor | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects from topical 2% Acetic acid and 1% Clotrimazole ear drops 3 days, 7 days, 14 days Symptoms reported by the participants and determined by the investigator to be drug-related adverse effects,Causative organisms of Otomycosis within 14 days identified from fungal and bacterial cultures of patients,Prevalence of concurrent bacterial infection in patients with otomycosis Within 14 days bacterial cultures | — |
Countries
Thailand
Contacts
Public ContactPornpawee Watjanarat
Khon Kaen University
Outcome results
None listed