impacted lower third molars Alveolar Ridge Preservation
Conditions
Interventions
Fresh venous blood from patients was used to collect autologous A PRF. They were divided into two clean 10 ml tubes without adding any anticoagulants, and they were centrifuged immediately using A PRF
temperature in the chamber21
speed: 150 *10rpm. Each A PRF clot was taken out of the tube after centrifugation and spited from the red element phase using scissors,
Fresh venous blood from patients was used to collect autologous
and speed: 230*10rpm. Each CGF clot was taken out of the tube after centrifugation and split from the red element phase using scissor.,Natural blood clot was used from Fresh venous blood as placebo.
Experimental Procedure/Surgery,Experimental Procedure/Surgery,Placebo Comparator No treatment
Advanced Platelet-Rich Fibrin,Concentrated Growth Factors,Natural blood clot
Sponsors
University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years. 2. Patients with completely or partially impacted lower third molars. 3. Patients who require surgical extraction. 4. Patients had no evidence of pericoronitis or periapical pathology. 5. Patients who are cooperative and able to attend follow-up visits. 6. Patients have no history of systemic disease or the use of systemic medications.
Exclusion criteria
Exclusion criteria: 1. pregnant or lactating women. 2. patients receiving non steroidal antiinflammatory drugs, anticoagulant therapy, or long term steroid treatment. 3. patients with systemic conditions that compromise immunity, such as diabetes mellitus, hypothyroidism, HIV infection, AIDS, severe liver disease, malnutrition, adrenal insufficiency, or Cushing's syndrome. 4. Smokers. 5. patients with pericoronitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Socket height and width within 24 hours after extraction, then after 3 months Cone-beam computed tomography (CBCT) | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain at first, third, and seventh days postoperatively Using Visual Analog Scale which ranges between 0 (no pain) and 10 (worst pain), facial swelling first, third, and seventh days postoperatively using flexible ruler to measure two distance; attachment of the ear lobe, and the corner of the mouth; and lateral canthus of the eye and mandibular angle | — |
Countries
Yemen
Contacts
Public ContactHeba Hail
University of Science and Technology
Outcome results
None listed