Assessment of Corneal Thickness in Glaucoma Patients Using Anterior Segment Optical Coherence Tomography

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20251028001

Enrollment

150

Registered

2025-10-28

Start date

2026-01-13

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Glaucoma, Corneal epithelial thickness, Anterior segment optical coherence tomography, Dry eye, Ocular surface disease

Interventions

Glaucoma patients diagnosed by glaucoma specialists using the structural evaluation, including disc photography and optical coherence tomography, and functional evaluation,Non-glaucoma patients (norma

Diagnostic,Diagnostic

Glaucoma,Non-Glaucoma

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age of 18 years and over 2. Glaucoma and non-glaucoma patients (diagnosed by glaucoma specialists using the structural evaluation, including disc photography and optical coherence tomography, and functional evaluation, i.e., visual field)

Exclusion criteria

Exclusion criteria: 1. Corneal pathology that affects the accuracy of corneal thickness measurement using AS-OCT, including corneal scar, corneal ectasia, pseudobullous keratopathy, corneal edema, and ocular surface neoplasm 2. Previous corneal surgery, i.e., corneal refractive surgery, corneal transplantation, not including cataract surgery with clear corneal incision 3. Previous glaucoma laser treatment, not including laser peripheral iridotomy 4. Previous glaucoma surgery 5. Bedridden status or patients who cannot perform OCT in a sitting position 6. Ocular and periocular infection

Design outcomes

Primary

Measure	Time frame
Corneal epithelial thickness At presentation Swept Source Optical Coherence Tomography (ANTERION and IOLMaster 700)	—

Secondary

Measure	Time frame
Ocular Surface Disease Index At presentation Ocular Surface Disease Index Questionnaire,Corneal stromal thickness At presentation Swept Source Optical Coherence Tomography (ANTERION and IOLMaster 700),Total corneal thickness At presentation Swept Source Optical Coherence Tomography (ANTERION and IOLMaster 700),Oxford corneal staining score At presentation Fluorescein-stained corneal photographs ,Intraocular pressure At presentation Goldmann applanation tonometer,Tear break up time At presentation Slit lamp examination,Meibomian gland function grading At presentation Slit lamp examination,Gonioscopy grading At presentation Slit lamp examination	—

Measure

Time frame

Ocular Surface Disease Index At presentation Ocular Surface Disease Index Questionnaire,Corneal stromal thickness At presentation Swept Source Optical Coherence Tomography (ANTERION and IOLMaster 700),Total corneal thickness At presentation Swept Source Optical Coherence Tomography (ANTERION and IOLMaster 700),Oxford corneal staining score At presentation Fluorescein-stained corneal photographs ,Intraocular pressure At presentation Goldmann applanation tonometer,Tear break up time At presentation Slit lamp examination,Meibomian gland function grading At presentation Slit lamp examination,Gonioscopy grading At presentation Slit lamp examination

—

Countries

Thailand

Contacts

Public ContactKitiya Ratanawongphaibul

Center of Excellence in Glaucoma, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University

kitiyaoph@gmail.com6622564142

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026