Comparing 25- and 15-Minute Pringle Maneuvers to Reduce Bleeding in Liver Surgery

Dose 25 minute Pringle's maneuver reduce blood loss during hepatectomy comparing to 15 minute? A randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20251026005

Enrollment

108

Registered

2025-10-26

Start date

2025-03-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Study about patients that has to hepatectomy and used pringle &#039

Interventions

we are clamp hepatoduodenum ligament 15 minute and off clam 5 minute(between hepatectomy),we are clamp hepatoduodenum ligament 25 minute and off clam 5 minute(between hepatectomy)

Active Comparator Procedure/Surgery,Experimental Procedure/Surgery

Pringle&#039

s maneuver 15 minute,Pringle&#039

s maneuver 25 minute

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients are more than 18 year olds 2.Patients consent to participate in the research. 3.Patient has indication for hepatectomy.

Exclusion criteria

Exclusion criteria: 1.Liver cirrhosis child B 2.Emergency liver surgery 3.patient has sign of portal hypertension 4.on steroid or immunosuppressive drug -coagulopathy disease

Design outcomes

Primary

Measure	Time frame
intraoperative blood loss in visit operation record form intraoperative blood loss	—

Secondary

Measure	Time frame
post operative liver injury follow up lab and clinical in post-operative day 1,2,3,5 and then follow up OPD case at 1,2,3 month follow up liver enzyne post op	—

Countries

Thailand

Contacts

Public ContactNATTHAWUT KANCHANAMETHAKUL

Ramathibodi hospital

nattawut757.k@gmail.com0855949877

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026