Transient Tachypnea of the Newborn Fetal lung volume, Pulmonary artery doppler, Transient Tachypnea of the Newborn
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancy 2. Gestation age at 37 weeks and more 3. Has signed the informed consent form to participate in the research 4. No congenital anomaly of lung and cardiac system
Exclusion criteria
Exclusion criteria: 1. Fetuses with congenital abnormalities of the cardiovascular or pulmonary systems, such as congenital pulmonary airway malformation (CPAM) or cardiac anomalies 2. Intrauterine infection or chorioamnionitis 3. Premature rupture of membranes (PROM) lasting more than 24 hours 4. Newborns with sepsis or pneumonia 5. Newborns diagnosed with pulmonary disease caused by respiratory dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| predicting transient tachypnea of the newborn (TTN) at GA more than 37 weeks Measure Three-dimensional fetal lung volume (3D-FLV) in combination with Doppler assessment of the pulmonary artery (PA-RI and PA-PI ) | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate AUC, cutoff value and accuracy of 3D-FLV, PA-RI, and PA-PI in predicting the occurrence of TTN diagnosed within the first 7 days after birth within 7 days post delivery evaluate the predictive ability (AUC) of fetal lung volume (3D-FLV), pulmonary artery resistance index (PA-RI), and pulmonary artery pulsatility index (PA-PI) in forecasting TTN | — |
Countries
Thailand
Contacts
Faculty of medicine, Srinakharinwirot university