Individuals with type 2 diabetes with peripheral artery disease. Type 2 diabetes, Peripheral artery disease, Functional capacity, Vascular function, Glycemic control.
Conditions
Interventions
Whole-body vibration training will be performed three times per week for 12 weeks at a frequency ranging from 15 to 27 Hz and an amplitude of 2 to 4 mm. Each training session will last approximately
Experimental Other,Active Comparator Other
Whole-body vibration training,Walking exercise
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Be diagnosed as type 2 diabetes mellitus 2. Have a formal PAD diagnosis (17) a. ankle-brachial index (ABI) equal or less than0.9 OR b. toe-brachial index (TBI) equal or less than 0.7 AND 3. Have PAD severity I-IIb according to the Fontaine classification system, i.e., ranging from asymptomatic to severe claudication while walking AND 4. Be aged equal or greater than 50 years.
Exclusion criteria
Exclusion criteria: 1. Symptomatic chronic heart failure according to a New York Heart Association functional class of III-IV (19); 2. Recent history of cardiovascular events within the previous 6 months (e.g., myocardial infarction, stroke, thrombosis); 3. Having undergone vascular surgery within the previous 6 months; 4. Having any other medical conditions for which WBVT would not be advisable, such as benign paroxysmal positional vertigo (BPPV); 5. Currently undergoing haemodialysis; 6. Ongoing pregnancy; 7. Inability to walk independently with both feet on the floor even with the use of assistance devices (e.g., crutches, walker, or cane); 8. Lower-limb amputees; 9. Having any cognitive impairment that would preclude the patient from following the WBV protocol appropriately and for the duration of the study, or from complying with the primary outcome assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional capacity At pre- and 12 weeks after intervention Incremental Shuttle Walk Distance in meter | — |
Secondary
| Measure | Time frame |
|---|---|
| Ankle-brachial index and Toe-brachial index At pre- and 12 weeks after intervention Ratio of blood pressure,Brachial artery flow-mediated dilation At pre- and 12 weeks after intervention Percentage of vascular diameter,Glycated hemoglobin At pre- and 12 weeks after intervention Percentage,Health-related quality of life At pre- and 12 weeks after intervention Score,Disease-specific health status At pre- and 12 weeks after intervention Score | — |
Countries
Thailand
Contacts
Public ContactSothida Nantakool
Chiang Mai University
Outcome results
None listed