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Correlation of Pupillometer-derived Parameters, the Critical Care Pain Observation Tool, and Numeric Rating Scale in Surgical Intensive Care Unit Patients

Correlation of Pupillometer-derived Parameters, the Critical Care Pain Observation Tool, and Numeric Rating Scale in Surgical Intensive Care Unit Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20251020001
Enrollment
100
Registered
2025-10-20
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Intensive Care Unit Patients Pupillometry, Critical-Care Pain Observation Tool, Numeric Rating Scale, Surgical Intensive Care Unit

Interventions

pain will be assessed using the NRS, obtained via verbal or non-verbal communication methods followed by pupillary response measurements using an automated pupillometer,pain will first be assessed us
Diagnostic,Diagnostic
communicable group,non-communicable group

Sponsors

Faculty of Medcine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Adults aged 18 years or older 2) Expected SICUs stay more than 24 hours 3) Intubated

Exclusion criteria

Exclusion criteria: 1) Quadriplegia 2) Use of neuromuscular blocking agents 3) Pre-existing pupil abnormality 4) Beta-blocker use 5) Other medications interfering with PLR

Design outcomes

Primary

MeasureTime frame
correlation coefficients between NRS and pupillometer-derived parameters in communicable patients ICU admission NRS score greater than or equal to 4,correlation coefficients between CPOT and pupillometer-derived parameters (PD, PLR, LAT, and VCPD) in non-communicable patients ICU admission COPT score greater than or equal to 3

Secondary

MeasureTime frame
the sensitivity and specificity of pupillometer-derived parameters (PD, PLR, LAT, and VCPD) for identifying moderate-to-severe pain, ICU admission NRS score greater than or equal to 4 and COPT score greater than or equal to 3

Countries

Thailand

Contacts

Public ContactAnnop Piriyapatsom

Faculty of Medicine Siriraj Hospital

annop.pir@mahidal.ac.th0922819241

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026