Pressure Ulcer Chronic Wound Wound Healing Calendula officinalis Silver sulfadiazine Herbal medicine Randomized controlled trial Elderly patients Anti inflammatory agents Wound care Traditional medicine
Conditions
Interventions
Participants will receive 5% calendula extract cream, manufactured by Thai Herbal Products Co., Ltd., in 100 g tubes. The product is standardized and quality-controlled with GMP PIC/S certification, I
Experimental Drug,Active Comparator Drug
Calendula,sulfadiazine
Sponsors
Office of the Thailand Science Research and Innovation (TSRI)
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Male or female patients aged 55 to 75 years 2.Patients who are willing to participate and able to provide written informed consent 3.Patients who are mentally competent and able to communicate and understand instructions 4.Patients with pressure ulcers up to stage 3 severity 5.Patients assessed by a physician as requiring non surgical treatment and without signs of active infection
Exclusion criteria
Exclusion criteria: 1.Patients currently receiving systemic antibiotic therapy either orally or intravenously for wound treatment 2.Patients with cancer at any stage 3.Patients with uncontrolled diabetes defined as HbA1c greater than 7.5 4.Patients with diabetic complications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing score Day 7, 14, 21, 28, 35, 42,49, 56, 63, and 70 Pressure Ulcer Scale for Healing (PUSH TOOL) | — |
Secondary
| Measure | Time frame |
|---|---|
| complication Day 7, 14, 21, 28, 35, 42,49, 56, 63, and 70 yes/no | — |
Countries
Thailand
Contacts
Public ContactNusriya Mooktaree
Division of Complementary and Alternative Medicine, Department of Thai Traditional and Alternative Medicine ,Ministry of Public health
Outcome results
None listed