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A Comparative Study of Mirogabalin versus Pregabalin as Preemptive Analgesics for the Attenuation of Postoperative Pain in Patients Undergoing Transforaminal Lumbar Interbody Fusion Surgery, randomized control trial

A Comparative Study of Mirogabalin versus Pregabalin as Preemptive Analgesics for the Attenuation of Postoperative Pain in Patients Undergoing Transforaminal Lumbar Interbody Fusion Surgery, randomized control trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20251010001
Enrollment
52
Registered
2025-10-10
Start date
2025-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To study the difference in pain levels at specified time intervals after surgery between the group receiving mirogabalin and the group receiving pregabalin (Pain score by visual analogue scale). Pre-emptive analgesia in TLIF surgery

Interventions

pregabalin 150 mg oral before surgery 1 hours,mirogabalin 7.5 mg oral before surgery 1 hours
Experimental Drug,Active Comparator Drug
patient who recieve pregabalin,patient who recieve mirogabalin

Sponsors

thammasat university hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Adult patient (age 20 - 80 years) 2. Patients scheduled for transforaminal lumbar interbody fusion 1-2 levels. 3. ASA classification I-II

Exclusion criteria

Exclusion criteria: 1. History of previous back surgery 2. BMI > 40 kg/m2 3. A history of allergy to gabapentinoid drugs.

Design outcomes

Primary

MeasureTime frame
Pain score after surgery 48 hours VAS score for pain—

Secondary

MeasureTime frame
the severity and limitations in daily activities 2, 4, 6, 12, 18, 24, 36, 48 hours after surgery Oswestry Disability Inde,Morphine Consumption 24, 48 hours milligram,Length of hospital stay - day—

Countries

Thailand

Contacts

Public ContactKoopong Siribumrungwong

Thammasat university hospital

koopongs@hotmail.com0902016565

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026