Vitamin D Deficiency in Chronic Myofascial Pain patients Vitamin D deficiency, chronic myofascial pain syndrome
Conditions
Interventions
The high-dose intervention group received four capsules of ergocalciferol 20,000 IU twice weekly (total 80,000 IU/week) for 8 weeks.,The standard-dose control group received two capsules of ergocalcif
Active Comparator Drug,Placebo Comparator Drug
High-dose intervention group,Standard-dose control group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Thai adults (18-65 years of age) who were diagnosed with chronic axial myofascial pain syndrome for more than 3 months with vitamin D deficiency (Vitamin D level < 20 ng/ml),whose pain numeric rating scale (NRS) was evaluated at four or greater.
Exclusion criteria
Exclusion criteria: 1.Received vitamin D supplement within 3 months before enrolment 2.Had a history of strong opioid use for pain control 3.had a history of fibromyalgia 4.Had other neurological diseases such as stroke, myelopathy, and radiculopathy 5.Had structural deformities such as scoliosis and discrepancy in limb length (LLD) 6.Had comorbidities that interfered with vitamin D absorption and metabolism such as osteoporosis, chronic kidney or liver disease 7. Had history usage of anticonvulsants and glucocorticoid 8. Pregnant or breastfeeding mothers, including women planning to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optimal vitamin D level At baseline and at 8 weeks after end of intervention Serum 25(OH)D level | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain reduction At baseline and at 8 weeks after end of intervention Numeric Rating Scale,The occurrence of adverse effects At 4 weeks and at 8 weeks after end of intervention Symptomatic adverse effects | — |
Countries
Thailand
Contacts
Public ContactChanakan Chuengmankhong
Phramongkutklao Hospital
Outcome results
None listed