bone resorption socket preservation Guided Bone Regeneration bone resorption bone regeneration
Conditions
Interventions
Following tooth extraction, an impression will be taken for the socket, then the chitosan membrane will be sutured with resorbable sutures after ensuring clot formation inside the socket. 4 months lat
chitosan/polyvinyl alcohol nanofibrous membrane ,blood clot
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1 patient who meets the ASA class I category. 2 patients aged between 18 - 65 years old. 3 patients who need at least 2 mandibular premolars extracted. 4 patients who are willing to participate in this clinical trial and attend all follow-ups.
Exclusion criteria
Exclusion criteria: 1 patient allergic to seafood or any of the membrane components. 2 patients with advanced periodontal disease, defined as probing pocket depth 5 millimeters or more with bleeding on probing at the extraction sites, or acute periapical infection at the extraction sites that cannot be fully debrided. 3 heavy smokers (more than 10 cigarettes per day). 4 alcoholics 5 pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Linear vertical bone height at surgery day and after 4 months calibrated periodontal probe will be used to measure the distance from the stent fixed reference holes to the alveolar crest at 4 specific points mid buccal mid lingual Mesial distal of the socket. ,Linear horizontal bone height at surgery day and after 4 months 3 fixed horizontal holes in the stent (1 mm,3mm,5mm) on buccal and lingual sides will be measured by graded probe,Bone density at surgery day and after 4 months percent of newly formed bone as seen in histologic sections.,Keratinized Tissue Width at 4th month re-entry distance in mm between gingival margin to the mucoginigival junction using the roll test | — |
Secondary
| Measure | Time frame |
|---|---|
| soft tissue healing 3rd and 7th post-extraction days Landry's healing scale,Soft Tissue Augmentation 4 months during re-entry surgery difference in mm between stent-to-bone distance and the stent-to-mucosa distance by graded probe,Adverse Events during the whole study period nature and severity of any harms will be reported as present or absent. | — |
Countries
Syrian Arab Republic
Contacts
Public ContactKhaldoun Darwich
Damascus university
Outcome results
None listed