Patients with maxillofacial abscess complicated by trismus indicated for surgery under general anesthesia High-flow oxygenation Conscious sedation Target-controlled infusion of propofol Maxillofacial abscess Trismus Flexible endoscope Fiberoptic intubation
Conditions
Interventions
Preoxygenation with HFNO at 30 L/min FiO2 1.0. After 5 minutes of preoxygenation, sedation was induced with TCI-propofol using the Schnider pharmacokinetic-pharmacodynamic model. The initial target ef
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
High flow nasal oxygen (HFNO), conscious sedation with target-controlled infusion (TCI) of propofol and topical anesthesia of the upper airway for difficult tracheal intubation via a flexible endosco
Sponsors
Vietnam Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adults aged 18 years or older 2. ASA physical status I, II, or III 3. Provided written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Patients requiring emergency airway management with insufficient time to perform tracheal intubation according to the study protocol 2. Severe cervical anatomical deformities preventing identification of the cricothyroid membrane as per the study protocol 3. Patients receiving anticoagulant therapy or with uncontrolled coagulopathy 4. Presence of cardiac arrhythmia or hypertension requiring treatment but not adequately controlled 5. Patients whose preoperative fasting interval for eating and drinking before surgery did not meet the required duration of at least 6 hours for solid food and at least 2 hours for clear fluids from the last eating and drinking intake 6. Pregnant women 7. Patients with neuropsychiatric disorders associated with impaired consciousness Withdrawal criteria: 1. Anaphylaxis or contraindications to study medications 2. Upper airway obstruction and/or tracheal stenosis with insufficient lumen to allow passage of the endotracheal tube 3. Patients who are uncooperative or unable to maintain the required position according to the study protocol 4. Patients in whom the study procedures are not performed fully and correctly as per protocol 5. Incomplete medical records
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to tracheal intubation Immediately after successful tracheal intubation second,Ease of tracheal intubation Immediately after successful tracheal intubation Ease of tracheal intubation according to Sethi,SpO2 During and immediately after tracheal intubation percent,PaO2 1 minute before and immediately after intubation mmHg,Time to glottic exposure Time to glottic exposure was defined as the time from insertion of the flexible endoscope into the nasal cavity to the point at which the glottis was reached and fully visualized Second,Adverse events Adverse events occurring before, during, and immediately after tracheal intubation were recorded. Adverse events occurring before, during, and immediately after tracheal intubation were recorded. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain level During and immediately after tracheal intubation Pain level according to the Analgesia/Nociception Index (ANI) | — |
Countries
Vietnam
Contacts
Public ContactLuan Nguyen
Vietnam Military Medical University
Outcome results
None listed