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Clinical improvement outcomes and Whole-Organ Magnetic Resonance Imaging scores following a Platelet-Rich Plasma injection for knee osteoarthritis

Clinical improvement outcomes and Whole-Organ Magnetic Resonance Imaging scores following a Platelet-Rich Plasma injection for knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250925002
Enrollment
19
Registered
2025-09-25
Start date
2024-05-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis OA knee

Interventions

The patients were recruited from the outpatient unit of the orthopedic clinic at Chulalongkorn Hospital. Knee MRI scans were planned for the patient prior to and following treatment, with the final s
Treatment
PRP treatment group

Sponsors

Chayanin Lertmahandpueti
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.patients aged 55 years or older 2.moderate pain (VAS > 3) at rest or at motion 3.knee standing radiographs graded 1-3 according to Kellgren and Lawrence

Exclusion criteria

Exclusion criteria: 1.patients who were unable to cooperate or refused to participate 2.who had received a knee injection within 3 months prior to the study 3.individuals with severe knee deformity defined as a standing tibiofemoral angle greater than 20 degrees 4.any contraindications to undergoing MRI, included the presence of an implanted cardiac pacemaker or defibrillator, internal pacing wires, or clips such as those used for cerebral, carotid, or aortic aneurysm

Design outcomes

Primary

MeasureTime frame
Whole-Organ Magnetic Resonance Imaging Score at 0, 6 months WORMS scoring system

Secondary

MeasureTime frame
Functional score at 0, 3 weeks, 6 weeks, 9 weeks, and 6 months Pain at rest, Pain at motion, WOMAC, 5 times sit-to-stand (5xSST), Timed Up and Go test (TUG), 3-minute walk tests (3MWT)

Countries

Thailand

Contacts

Public ContactChayanin Lertmahandpueti

Ratchapipat Hospital

chayanin.lert@gmail.com021024222

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026