The study enrolled twelve healthy volunteers. traditional medicine, untargeted metabolomics, proteomics, LC-MS, piperine, herbal supplementation
Conditions
Interventions
Participants took one 500 mg capsule of TKT orally three times daily (before breakfast, lunch, and dinner) for a duration of 7 days. ,Participants took one 500 mg capsule of cornstarch orally three ti
Experimental Dietary Supplement,Placebo Comparator Dietary Supplement
Tri-Ka-Tuk (TKT) group,placebo group
Sponsors
Thailand Science Research and Innovation (TSRI)
Eligibility
Sex/Gender
All
Age
25 Years to 59 Years
Inclusion criteria
Inclusion criteria: (1) aged between 25 and 59 years, (2) included both male and female participants, (3) proficient in reading, writing, speaking, and listening in Thai, (4) no prior history of adverse reactions to any components of the Tri-Ka-Tuk formula, specifically ginger, pepper, long pepper, or corn, and (5) good general health as confirmed by a comprehensive physical examination and medical history assessment conducted by a qualified physician
Exclusion criteria
Exclusion criteria: (1) Presenting with fever exceeding 37.5 C (2) Current use of medications including rifampicin, theophylline, propranolol, or phenytoin (3) Pregnancy, lactation, or actively preparing for pregnancy (4) Current use of oral contraceptives (5) Habitual consumption of alcohol or tobacco products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in plasma biomedical characteristics Baseline and Day 7 Automated biochemical analyzer | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in metabolomes and proteomes Baseline and Day 7 LC-MS | — |
Countries
Thailand
Contacts
Public ContactPariyapat Singthong
Faculty of Thai Traditional and Alternative, Ubon Ratchathani Rajabhat University
Outcome results
None listed