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Prevalence of abnormal cerebroplacental ratio in obesity during pregnancy and correlation with adverse perinatal outcomes

Prevalence of Abnormal Cerebroplacental Ratio in Obesity during Pregnancy and Correlation with Adverse Perinatal Outcomes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250924002
Enrollment
200
Registered
2025-09-24
Start date
2025-09-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The RATIO37-Trial has provided evidence that considering CPR in clinical decision making about planned delivery at term can reduce neonatal morbidity, especially neonatal neurological morbidity, compared to fetal growth assess- ment alone low CPR has been proven to predict operative delivery for intrapartum fetal compromise

Interventions

Obesity during pregnancy (BMI greater than or equal to 25, Asia-Pacific criteria)
Health Services Research
Obese pregnant women

Sponsors

Bhumibol Adulyadej Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1.Singleton pregnancy 2.Pre-pregnancy BMI greater than or equal to 25 3.Gestational age greater than or equal to 37 weeks 4.Provide informed consent

Exclusion criteria

Exclusion criteria: 1. Elective cesarean section 2.Fetal growth restriction (FGR) 3.Fetal anomalies or genetic disorders 4.Maternal comorbidities affecting vasculature (HTN, DM, autoimmune disease, CKD) 5.Placental or umbilical cord abnormalities (e.g., abruption, single umbilical artery)

Design outcomes

Primary

MeasureTime frame
Prevalence of abnormal cerebroplacental ratio in obese pregnant women at term at perinatal outcomes Doppler ultrasound of Middle Cerebral Artery Pulsatility Index (MCA PI) and Umbilical Artery Pulsatility Index (UA PI)

Secondary

MeasureTime frame
Correlation between abnormal CPR and adverse perinatal outcomes at delivery documented by intrapartum/postpartum monitoring or emergency delivery indication or observed at delivery

Countries

Thailand

Contacts

Public ContactTanita Chardleelahar

Department of Obstetrics & Gynecology, Bhumibol Adulyadej Hospital, Bangkok, Thailand

chardleelahartanita@gmail.com66819043291

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026