The RATIO37-Trial has provided evidence that considering CPR in clinical decision making about planned delivery at term can reduce neonatal morbidity, especially neonatal neurological morbidity, compared to fetal growth assess- ment alone low CPR has been proven to predict operative delivery for intrapartum fetal compromise
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Singleton pregnancy 2.Pre-pregnancy BMI greater than or equal to 25 3.Gestational age greater than or equal to 37 weeks 4.Provide informed consent
Exclusion criteria
Exclusion criteria: 1. Elective cesarean section 2.Fetal growth restriction (FGR) 3.Fetal anomalies or genetic disorders 4.Maternal comorbidities affecting vasculature (HTN, DM, autoimmune disease, CKD) 5.Placental or umbilical cord abnormalities (e.g., abruption, single umbilical artery)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of abnormal cerebroplacental ratio in obese pregnant women at term at perinatal outcomes Doppler ultrasound of Middle Cerebral Artery Pulsatility Index (MCA PI) and Umbilical Artery Pulsatility Index (UA PI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between abnormal CPR and adverse perinatal outcomes at delivery documented by intrapartum/postpartum monitoring or emergency delivery indication or observed at delivery | — |
Countries
Thailand
Contacts
Department of Obstetrics & Gynecology, Bhumibol Adulyadej Hospital, Bangkok, Thailand