EGD Esophagogastroduodenoscopy Colonoscopy Gag reflex Ketamine Lidocaine EGD Esophagogastroduodenoscopy Colonoscopy Gag reflex Adults Lidocaine Ketamine
Conditions
Interventions
Participants in this group will receive standard induction with propofol 2-2.5mg/kg IV via TCI, and fentanyl 50 mcg IV (or 25 mcg if aged more than or equal to 65 years and/or weighing equal or less t
Control,Lidocaine,Ketamine
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1 Adult patients aged between 18 and 75 years old 2 Undergoing elective EGD with or without colonoscopy
Exclusion criteria
Exclusion criteria: 1 Patient refusal to participate 2 Known allergy or contraindication to ketamine, or fentanyl 3 ASA physical status classification of greater than III 4 Patients with respiratory, haemodynamic, or neurologic impairment, identified by signs of respiratory distress, SBP less than 90 mmHg or SBP/DBP of more than 160/90, or a Glasgow Coma 5 Score less than 15 6 Patients with a body weight less than or equal to 40kg 7 Patients with body mass index (BMI) more than 30 kg/m2 8 Patients with cognitive impairment, communication limitations and/or lack of decision-making capacity 9 Pregnant or lactating women 10 Patients with severe gastrointestinal disorders (e.g., active GI bleeding, recent GI surgery) or those with with a full stomach, ascites, or inadequate NPO time 11 Patients with active psychosis 12 Patients with a suspected or confirmed current or past history of narcotic abuse or potential for secondary gain 13 Patients who require intubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough and gag reflex Intraoperative Cough and gag reflex will be assessed by the endoscopists using the Cough and Gag Score when a vomiting-like response is elicited upon insertion of the endoscope | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications, recovery time, Ramsey Sedation score, Surgeon and Patient satisfaction score Intra-operative and immediately post-operative in PACU at 5, 10, 15 and 20 minutes post-op Complications will be documented and Ramsey sedation score as well as patient and surgeon satisfaction score will be done via a Likert scale | — |
Countries
Thailand
Contacts
Public ContactPhornnapat Utenpattanun
Khon Kaen University
Outcome results
None listed