Advanced osteoarthritis of the knee in patients who required unilateral total knee replacement. dual subsartorial block, local infiltration analgesia, postoperative pain control, total knee replacement, knee osteoarthritis, multimodal analgesia
Conditions
Interventions
In this group, the surgeon will perform LIA for the operated knee with the cocktail regimen composed of bupivacaine 200 mg plus ketorolac 60 mg and adrenaline 0.03 mg diluted with NSS to a total of 15
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
LIA,DSB
Sponsors
Faculty of Medicine, Khon Kaen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo unilateral TKR under spinal anesthesia 2. Age over 18 years 3. ASA physical status 1-3
Exclusion criteria
Exclusion criteria: 1. Refuse to participate 2. Previous knee surgery or redo-surgery 3. Allergy or contraindicate to study drugs, paracetamol, morphine, ketorolac, or bupivacaine 4. Body weight less than 35 kg 5. PNB contraindications include skin infection at the block site, and coagulopathy 6. Inability to cooperate, communicate, or report pain scores.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain score at 24 hour after surgery postoperative at PACU, 6h, 12h, 24h, 36h, and 48h. Numeric rating pain score (patient self-report their pain intensity using 11-point scale from 0-10) | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative morphine consumption postoperative at PACU, 6h, 12h, 24h, 36h, and 48h. total morphine consumption (mg) | — |
Countries
Thailand
Contacts
Public ContactPuntira Chitto
Faculty of Medicine, Khon Kaen University
Outcome results
None listed