Skip to content

Evaluation of Different Clinical Approaches in the Healing of Aphthous Ulcers

Evaluation of Different Clinical Approaches in the Healing of Aphthous Ulcers

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250917012
Enrollment
80
Registered
2025-09-17
Start date
2025-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A mouth ulcer (also called an oral ulcer or mucosal ulcer) is an ulcer that forms on the mucous membrane of the mouth. Mouth ulcers are very common and occur in many different diseases and by many different mechanisms. 2022 ICD-10-CM Diagnosis Code K12.30 MeSH Code: D019226

Interventions

In the control group (20 patients), measurements will be taken on days 1, 3, 7, 10, and 14. Patients will not receive any treatment. They will be provided with dietary recommendations (including oral
No Intervention No treatment,Experimental Drug,Experimental Device,Experimental Drug
control group,Vitamin E group,photobiomodulation group,Vitamin E+Photobiomodulation group

Sponsors

Cennet Neslihan EROGLU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1)Patients with aphthous ulcers on the alveolar crest, inner lip, tongue, sublingual, gingiva, inner cheek, hard palate, or floor of mouth 2)Age between 18 and 45 3)ASA Class I individuals 4)Presentation within 2 days of the lesion

Exclusion criteria

Exclusion criteria: 1)Patients who are pregnant or lactating 2)Smoking patients 3)Patients with systemic diseases 4)Having an orthodontic or prosthetic appliance 5)Having periodontitis 6)Having received previous treatment 7)Having received steroid treatment or anti-inflammatory medication within the last 3 months 8)Having had an infectious disease or active infectious lesions within the last 3 months

Design outcomes

Primary

MeasureTime frame
Reducing VAS scores in aphthous ulcer patients. 12 months after the end of the intervention Visual Analog Scala

Secondary

MeasureTime frame
treatment effects 12 months after the end of the intervention Investigators Global Improvement Scale

Countries

Turkey

Contacts

Public ContactCennet Neslihan Eroglu

Akdeniz University

dt.ozeryayla@gmail.com05326084485

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026