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Comparative Effectiveness of Early-Line versus Late-Line Eribulin Treatment for Metastatic Breast Cancer: A Target Trial Emulation with Propensity Score Analysis

Comparative Effectiveness of Early-Line versus Late-Line Eribulin Treatment for Metastatic Breast Cancer: A Target Trial Emulation with Propensity Score Analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250917001
Enrollment
30
Registered
2025-09-17
Start date
2025-09-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer patients who were treated with early or late line eribulin eribulin, breast cancer, survival, target trial emulation, propensity score

Interventions

The early line group included those who received eribulin as first to third line therapy,The Late line group included those who received eribulin as fourth or more line therapy
Treatment,Treatment
Early line eribulin,Late line eribulin

Sponsors

None listed

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: women aged 18 years or older with histologically confirmed breast cancer and documented metastatic disease who received at least one cycle of eribulin during the study period.

Exclusion criteria

Exclusion criteria: Patients were excluded if baseline clinical data were incomplete or if eribulin was administered in the adjuvant or neoadjuvant setting.

Design outcomes

Primary

MeasureTime frame
overall survival after receiving eribulin treatment hazard ratio

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactChaichana Chantharakhit

Buddhasothorn hospital

chaichana.md@gmail.com0817866945

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026